objectivethis study aims to investigate the relationship between oxidative balance score (obs) and vision-related functional burden (vrfb) in us adults.metho...
villanova university is a catholic university founded in 1842 by the order of saint augustine. at villanova, our educational experience is rooted in a passionate, collaborative pursuit of knowledge and service to others.
background colistin is a polymyxin antibiotic which has been used for treatment of gram-negative infections, but it was withdrawn due to its nephrotoxicity. however, colistin has gained its popularity in recent years due to the reemergence of multidrug resistant gram-negative infections and drug-induced toxicity is considered as the main obstacle for using this valuable antibiotic. results in total, 30 articles, including 29 animal studies and one clinical trial were included in this study. these compounds, including aged black garlic extract, albumin fragments, alpha lipoic acid, astaxanthin, baicalein, chrysin, cilastatin, colchicine, curcumin, cytochrome c, dexmedetomidine, gelofusine, grape seed proanthocyanidin extract, hesperidin, luteolin, lycopene, melatonin, methionine, n-acetylcysteine, silymarin, taurine, vitamin c, and vitamin e exhibited beneficial effects in most of the published works. conclusions in this review, the authors have attempted to review the available literature on the use of several compounds for prevention or attenuation of colistin-induced nephrotoxicity. most of the studied compounds were potent antioxidants, and it seems that using antioxidants concomitantly can have a protective effect during the colistin exposure.
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clinmed international library is an open access publisher of more than 50 journals covering the major disciplines of clinical medicine. the main aim of clinmed journals is to serve as an open repository for all the latest research updates in the multidisciplinary fields of medical and clinical sciences. all the clinmed journals are bound to the policies of open access and peer review system.
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about biomedicine and the philosophy of the zabrecky institute of biomedicine located in villanova, pa.
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vitamin d (vd), a crucial micronutrient, regulates bone health and immune responses. recent studies suggest that vd may confer protective effects against chronic inflammatory diseases. additionally, plant-based peptides can show biological activities. furthermore, the supplementation of protein hydr …
bioglasses/ceramics/other hard materials v1. adsorption behavior of serum proteins on the surface of hydroxyapatite ceramics with preferred orientation to a-plane, erika onuma, graduate school of science and technology, meiji university, onuma@meiji.ac.jp
anthony j bazzan md is jefferson health affiliate clinician dr. bazzan is medical director of the marcus institute of integrative health- jefferson health, and clinical assistant professor in the department of integrative medicine and nutritional sciences, thomas jefferson university. dr. bazzan is a pioneer in intravenous micronutrient therapies, including iv vitamin c. he is one of the country’s top doctors for bio-identical hormone replacement for women and men. dr. bazzan is board-certified in internal medicine, integrative and holistic medicine, and is fellowship trained in geriatric medicine. he is a fellow of the american college of nutrition and a scientific member of the sydney kimmel cancer center. dr. bazzan has a national reputation for solving and treating “medical mysteries”.
dietetic interns are required to write an article in the graduate-level advanced nutrition course about a topic that is of interest to their selected audience. these articles are published here so that our students' interests can be explored and the quality of their work observed. browse the topics below: beverages
it is the position of the academy of nutrition and dietetics that micronutrient supplements are warranted when requirements are not being met through the diet alone. those with increased requirements secondary to growth, chronic disease, medication ...
using neuro-nutrient therapy, jen can help people with anxiety, insomnia, stress management & food issues address underlying brain chemistry deficiencies.
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psoriasis represents an immune-mediated disease with an unclear cause that’s marked by inflammation triggered by dysfunction in the immune system, which results in inflammation in various parts of the skin. there could be obvious symptoms, such as elevated plaques; these plaques may appear differently depending on the type of skin. this disease can cause inflammation in the elbows, lower back, scalp, knees, or other regions of the body. it can begin at any age, although it most commonly affects individuals between the ages of 50 and 60. specific cells (such as t cells) have been observed to play an obvious role in the pathogenesis of psoriasis, in addition to specific immunological molecules such as tnf-, il-12, il-23, il-17, and other molecules that can aid in the pathogenesis of psoriasis. so, during the past two decades, biologists have created chemical drugs that target these cells or molecules and therefore prevent the disease from occurring. alefacept, efalizumab, adalimumab, ustekinumab, and secukinumab are a few examples of chemical drugs. it was discovered that these chemical drugs have long-term side effects that can cause defects in the patient's body, such as the development of the rare but life-threatening disorder progressive multifocal leukoencephalopathy (pcl). its rapidly progressive infection of the central nervous system caused by the jc virus and other drugs may cause increased production of neutralising anti-drug antibodies (ada) and the risk of infusion reactions like pruritus, flushing, hypertension, headache, and rash. so, our context intends to talk in our review about natural products or plants that may have therapeutic characteristics for this disease and may have few or no side effects on the patient's body.
author(s): tylavsky, frances a; han, luhang; taylor, lauren m sims; mason, w alex; carroll, kecia n; bush, nicole r; lewinn, kaja z; melough, melissa m; hartman, terryl j; zhao, qi | abstract: the objective of this study was to calculate an oxidative balance score (obs) utilizing diet and lifestyle information collected from 1322 women during the second trimester of pregnancy in the conditions affecting neurocognitive development and learning in early childhood study. an energy-adjusted obs was calculated using nutrient information from a food frequency questionnaire (ffq), lifestyle measures, and plasma folate and vitamin d levels. using the least absolute shrinkage and selection operator method, 91 food items from the ffq were selected and they accounted for 82% of the variance in the obs, with cruciferous vegetables, citrus fruits, fruit juice, and coffee being among the highest anti-oxidant predictors, and red meats and alcohol among the highest pro-oxidant contributors. urinary f2-isoprostane, an objective indicator of oxidative stress, was lower with increasing obs quintiles in a stairstep manner (p for trend = 0.0003), suggesting the possible utility of the obs as an indicator of oxidative stress. the obs was moderately correlated with the healthy eating index (correlation coefficient = 0.6076), suggesting it provides a distinct measure of a healthy diet. in conclusion, the obs may serve as a valid reflective indicator of urinary f2-isoprostanes and an epidemiological tool to inform intervention studies, in order to minimize oxidative stress during pregnancy.
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