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and liver injuries tied to herbal and dietary supplements are on the rise, data show
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five new cases of jaundice have been associated with the regular consumption of turmeric supplements and teas, with all cases recovering after treatment
a rutgers analysis showed that early signs of liver damage from high-dose green tea extract were somewhat predicted by one variation in a genotype and strongly predicted by another variation.
herbal-induced liver injury (hili) continues to increase in prevalence each year due to the ongoing popularity of herbal supplements and complementary and alternative medicines. a detailed literature review of case reports and clinical studies published from march 2021 to march 2023 was performed. we discuss the epidemiology and diagnosis of hili as well as the current and proposed laws and regulations. the 2021 acg guidelines and 2022 aasld practice guidelines for the diagnosis and management of drug and herbal-induced liver injury are discussed. we describe updates to previously reported etiologies of hili such as ayurveda, ashwagandha, turmeric, kratom, green tea extract, and garcinia cambogia. newly described supplements resulting in hili, such as tinospora cordifolia, horse chestnut, alkaline water, and more, are described. we discuss newly and previously identified hepatoprotective herbal supplements as they have been reported in the study of animal models and human liver cells. this review suggests the need for ongoing research on the causes and mechanisms of hili to ensure its proper diagnosis, prevention, and treatment in the future. the goal of this review is to provide novice and expert readers with knowledge regarding the possible etiologies of hili and a general overview.
a study in jama network open reveals a rise in drug-induced liver injuries associated with herbal supplements like green tea extract, turmeric, ashwag
dr. jim keany, co-director of the emergency room at mission hospital in mission viejo, joins the bill handel show for 'medical news'! dr. keany talks with wayne about 6 potential herbal supplements linked to liver risks, how vitamin d helps, cheek swabs predicting risks of death, and time restricted eating.
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herbal and dietary supplements represent a multi-billion-dollar industry reportedly used by over half of american adults. however, these products are not regulated by the federal drug agency and contain a wide range of contaminants, leading to over 50,000 adverse events each year. this review aims to highlight the widespread use and current regulatory status of herbal and dietary supplements, identify the presentation and diagnostic dilemmas faced with liver injury, and discuss the most common agents implicated in herbal and dietary supplement hepatotoxicity.
turmeric is a popular herb derived from the roots of the plant curcuma longa found mostly in india and southern asia. turmeric has an intense yellow color and distinct taste and is used as a dye as well as a spice in the preparation of curry. turmeric and its purified extract curcumin are also used medically for their purported antiinflammatory and antioxidant effects to treat a wide variety of conditions and for general health and wellness. turmeric and curcumin have been associated with a low rate of transient serum enzyme elevations during therapy and, while having a long history of safety, turmeric products have recently been implicated in several dozen instances of clinically apparent acute liver injury.
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researchers are concerned that liver injuries from turmeric supplements could be on the rise. here's what we know about why that may be the case, and how to determine if you should keep turmeric in your wellness routine.
green tea contains antioxidants and other health-promoting compounds that may boost brain health, support heart health, and protect against certain cancers. learn more about green tea's health benefits, side effects, and how to prepare it.
hepatitis b virus (hbv) is endemic in many parts of the world and is a significant cause of
it’s rumored that green tea and grapefruit juice can help detox your liver. do they work? a physician reviews a list of the best drinks for your liver.
find out if there is risk of liver damage from supplements such as green tea, niacin, red yeast rice and vitamin a.
your liver works hard to rid your body of toxins. this six-step liver cleanse recipe helps revitalize your liver and boost your health.
more than 15 million americans may be putting their liver health at risk, simply by trying to better their overall health. new research has revealed the extent of the damage being caused by taking popular botanical supplements including turmeric, green tea, the stress-relieving ashwagandha and…
a study in jama network open reveals that 5% of u.s. adults consume six potentially hepatotoxic botanicals, highlighting a significant need for increased regulatory oversight.
doctors have raised concerns about the safety of taking turmeric and black pepper supplements after discovering a small group of patients have experienced liver injury.
turmeric has been used in ayurvedic medicine to treat various conditions. here's what you should know about its benefits, dosage, and adverse effects.
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“we weren’t aware that so many people were taking these supplements,” dr. alisa likhitsup, a clinical assistant professor of medicine and lead author of the research.
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some common herb & dietary supplements may cause liver damage. so can many medications. protect yourself by knowing early signs of danger!
look up information about prescription drugs, over-the-counter medications, herbs, vitamins and supplements.
an estimated 15.6 million adults in the united states consumed at least one potentially hepatotoxic botanical product in the past 30 days, with turmeric and green tea being the most common.
types of therapies used in complementary and alternative medicine (cam) in cancer care, such as mind-body methods like meditation and yoga, or biologically-based like herbs and vitamins. massage, reiki, acupuncture, and traditional medical systems are included. also mentioned are talking to your doctor about cam and the safety of cam.
herbal teas are made from tisanes, which are blends or infusions of dried fruits, flowers, spices or herbs in water. tisanes have been shown to offer medicinal effects....
"we estimated that at least 15.6 million u.s. adults used at least 1 of 6 potentially hepatotoxic botanical products within the past 30 days," the authors wrote.
there remain liver-related safety concerns, regarding potential hepatotoxicity in humans, induced by green tea intake, despite being supposedly beneficial. although many randomized controlled trials (rcts) of green tea extracts have been reported in the literature, the systematic reviews published to date were only based on subjective assessment of case reports. to more objectively examine the liver-related safety of green tea intake, we conducted a systematic review of published rcts. a systematic literature search was conducted using three databases (pubmed, embase and cochrane central register of controlled trials) in december 2013 to identify rcts of green tea extracts. data on liver-related adverse events, including laboratory test abnormalities, were abstracted from the identified articles. methodological quality of rcts was assessed. after excluding duplicates, 561 titles and abstracts and 119 full-text articles were screened, and finally 34 trials were identified. of these, liver-related adverse events were reported in four trials; these adverse events involved seven subjects (eight events) in the green tea intervention group and one subject (one event) in the control group. the summary odds ratio, estimated using a meta-analysis method for sparse event data, for intervention compared with placebo was 2.1 (95% confidence interval: 0.5–9.8). the few events reported in both groups were elevations of liver enzymes. most were mild, and no serious liver-related adverse events were reported. results of this review, although not conclusive, suggest that liver-related adverse events after intake of green tea extracts are expected to be rare.
“just because it’s an herb doesn’t mean it’s risk-free.”
an estimated 5% of u.s. adults have consumed at least one potentially hepatotoxic herbal supplement in the past month, raising concerns about liver health risks associated with unregulated botanical products.