Okay, so, at the end of NTN, John is drawing initials in the sand, right? They are as follows

JE- John ???

JA- John Alecto

JH- John Harrow (?)

So Blood of Eden, right? This can refer to the bloodline of humans who escaped earth, a proverbial Eden. Or it could be interpreted much more literally as those descended from someone named Eden. E.

JE. John+Eden

Anyway, what if John ended the world because his ex-wife was on one of those ships