Some people seem to think that Gamzee went crazy because he ran out of sopor slime. I've always theorized that it was because due to his blood color that he was always unpredictable and the slime only pacified him, or that lil cal told him to murder his friends. Which one of these is true????????

There are several things that contributed to Gamzee’s homicidal spree. He is violent by nature and the sopor slime was acting as a pacifier so running out of that was one.  Lil Cal and Doc Scratch were another. Viewing the blasphemous ICP video was also one