So, would Omega Flowey in Axetale be easier to defeat than he was in the game? He doesn't have the full power of the six souls and he's a complete lunatic. I think that once Aliza has a good grip on her magic she'd be able to face him. She'll have to do it in one shot, though. Flowey's going to be playing for keeps.

Unfortunately not. Flowey’s lack of sanity and loss of souls only makes him more dangerous. He’s desperate, now, and unhinged, saying nothing of still holding the power over resets. It still is not possible to defeat him by conventional means, and there are no souls of determination present to call to his imprisoned souls for help. They cannot hear, and so obey the will of the fiend.

If Aliza ever faced him, it would be to her own end.